{"product_id":"la-clinica-pure-retinol-1-in-luxurious-plant-oils-30ml","title":"La Clinica Pure Retinol 1% in Luxurious Plant Oils 30mL","description":"\u003cp\u003e\u003cspan\u003eThe most researched non-prescription Vitamin A derivative in a lightweight, fast penetrating, sensorially luxurious oil format. Stabilised with Lipochroman and Vitamin E. Boosted with Tetrahydropiperine. Soothed with Defensil Plus and calming extracts of Chamomile and Calendula. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eFormulated to help rejuvenate the appearance of the skin and give an overall improvement to skin texture. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eManufactured \/ packaged under nitrogen, into airless containers. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eAs we age our skin experiences a number of physiological changes such as thinning of the dermis and epidermis as well as a reduction in keratinocytes and collagen production. In addition to natural ageing, the skin is repeatedly exposed to environmental stressors such as UV radiation, pollution etc. Thinning of the dermis and epidermis results in a less effective skin barrier function and in turn leads to higher environmental stressors, higher trans-epidermal water loss and vulnerable skin. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eRetinol exhibits powerful anti aging action by increasing the production of keratinocytes (cells which produce keratin), endothelial cells (increases dermal vascularity) and fibroblasts (synthesizes collagen and extracellular matrix). \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eThis in turn leads to:\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Thickening of the epidermis\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Stimulation of collagen production\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Increase in skin firmness\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Increase in cellular renewal\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Decrease in fine lines and wrinkles\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBenefits of Retinol:\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Retinol has shown to inhibit UV induced Matrix Metalloproteinases (enzymes which degrade collagen and prevent new collagen production).\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Regulate oil production and reduce acne\/blemishes.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Reduce collagenase.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e -Brightens skin tone.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e -Evens out skin tone.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Increases wound healing.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Considerably less erythema, irritation, TEWL, compared to tretinoin \/ retinoid acid.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e- Retinol boosts the effects of hydroxy acid peels due to increased cellular renewal, increased epidermal healing and enhanced penetration of the peeling agent. Retinol can be resumed after all evidence of peeling and irritation subsides.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eReferences:\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• J Invest Dermatol. 1995;105:549–56.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Skin Res Technol. 1998 Nov;4(4):237-43.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Nature. 1996 Jan 25;379(6563):335-9.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• N Engl J Med. 1997 Nov 13;337(20):1419-28.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Journal of Cosmet Dermatol. 15, 49-57\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Clin Cosmet Investig Dermatol. 2015 Aug 26;8:455-61.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Arch Dermatol. 2007;143(5)606-12\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Int J Cosmet Sci. 2017 Feb 39(1)56-65\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• J Invest Dermatol. 1996 Aug;107(2):178-82.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• Skin Res Technol. 1998 Nov;4(4):237-43.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003e• J Invest Dermatol. 2000 Mar;114(3):480-6.\u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cb data-mce-fragment=\"1\"\u003eWarning\u003c\/b\u003e\u003cspan\u003e – May cause irritation. Skin may also start to shed dead skin cells within the first week and may last a further week. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eAvoid direct and unprotected exposure to sun. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eDO NOT use during pregnancy. \u003c\/span\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cspan\u003eDO NOT use on sensitive skin conditions.\u003c\/span\u003e\u003c\/p\u003e","brand":"Beautè Beauty Clinic Shop","offers":[{"title":"Default Title","offer_id":45354085810223,"sku":null,"price":0.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0762\/5844\/3311\/files\/LCE5D_460x622_2x_ae693937-5c9f-4b54-b384-a5fef527c803.webp?v=1778796485","url":"https:\/\/beaute-beauty-clinic-shop.myshopify.com\/products\/la-clinica-pure-retinol-1-in-luxurious-plant-oils-30ml","provider":"Beautè Beauty Clinic Shop","version":"1.0","type":"link"}